Peptides for Skin

If you haven’t heard about the use of peptides in skin care products, we’re going to tell you what you’ve been missing. Peptides have come a long way and the new research about how they benefit skin is remarkable. Some of the information out there is overblown, but other aspects of peptides for skin deserve your attention. Here’s the facts versus fiction.

What Are Peptides?

First, we need to start with the science: Peptides are fragments of proteins. On their own, peptides are made up of amino acids. When amino acids are combined in certain formations they create specific peptides (and there are hundreds of peptides), and when peptides are formed in a certain way, they make specific proteins.

Proteins are the fundamental building blocks of skin. Without peptides, skin doesn’t remain intact and the result is loss of firmness, appearance of wrinkles, texture changes, and skin that doesn’t bounce back as it once did.

What’s so fascinating about peptides is that abundant research has clearly shown that each of them works in very specific ways to target an exact skin care need. They also teach skin to do what’s required to help revitalize these building blocks, which can help revive aging skin.

Peptides in Skin Care: A Balanced View

Although there are intriguing reasons to consider peptides as a significant part of a skin care formula as we did with our unique Peptide Booster, we also want you to know there’s a lot of hype around what they can do. Sadly, the hype is often completely blown out of proportion. Peptides can do amazing things for skin, but they do not replace what cosmetic corrective procedures can do, as many companies have claimed over the years.

There’s no single ingredient solution for all the signs of aging and other skin problems we endure, and peptides are no exception. You would be cheating your skin to think that any single peptide (or any other specific skin care ingredient) is your skin’s solo rescuer. We use this multi-ingredient “cocktail” approach when we formulate all Paula’s Choice Skincare products, including our Peptide Booster, which contains a mix of eight distinctive peptides, several amino acids, and skin-replenishing ingredients.

Promising new research has us excited about using peptides in skin care products. Their ability to help revitalize skin’s building blocks so it becomes more resilient is a wonderful asset for skin, but keep your expectations realistic, or you will be disappointed.

Peptides Need Friends

What’s most important for you to keep in mind is that as special as peptides are, they need “friends” in the form of supporting ingredients to help address all the needs of skin. Any skin care formula worthy of your hard-earned dollars must include the specialized ingredients we talk about all the time such as antioxidants, skin-replenishing ingredients, and skin-restoring-ingredients (which includes peptides). Peptides can do a lot on their own, but they can’t do it all alone.

As a reminder (because it’s so important), when peptides are blended with antioxidants, skin-soothing ingredients, and skin-replenishing ingredients they can address multiple signs of aging and you will love the results!

Copper Peptide: Fact or Fiction

Speaking of a single skin care ingredient being overly-hyped, copper peptide is certainly one of them. The spin begins with the notion that skin’s building blocks are assembled by copper. So, the logic would follow that you must have copper peptide in your skin care products to get that benefit. Although it’s true copper peptide is a skin-restoring ingredient, there are lots of other peptides with equally, if not more impressive, properties.

To keep it in perspective, although there are studies showing the dramatic positive effects of copper peptide those studies rarely, if ever, compare copper peptides to other peptides or other ingredients like potent antioxidants. It’s important to realize that many ingredients have extraordinary research proving their value for skin, not just copper peptide. That’s the pitfall of getting too wrapped up in one single ingredient. Skin care isn’t that simple!

Ironically there’s also research about copper being potentially toxic to skin. However, this research is mostly about pure copper in the body not as a peptide applied to skin. The negative effects are about what happens when copper is out of balance, meaning too much copper is present.

Peptide Skin Care: The Bottom Line

Peptides can be a great addition to your skin care routine because they can address so many skin concerns. But as with all anti-aging ingredients, the best approach is to use products such as moisturizers and serums that use a cocktail of great ingredients, including antioxidants and skin-restoring substances (plus daily broad-spectrum sunscreen) to visibly improve the health and appearance of your skin!

Learn more about boosters.

References for this information:
Cosmetics, May 2017, pages 1-14
ChemMedChem, August 2016, issue 16, pages 1850-1855
Bulletin of Experimental Biology and Medicine, May 2016, issue 1, pages 175-178
Journal of Drugs in Dermatology, April 2016, supplemental, pages 63-71
Austin Journal of Pharmacology and Therapeutics, August 2014, pages 1-9
Biological Trace Element Research, August 2013, issue 2, pages 268-274
Clinical Chemistry and Laboratory Medicine, April 2013, pages 1–8
Dermato Endocrinology, July 2012, issue 3, pages 308–319

Skincare Alphabet: C Is For Copper

What is it?

Copper peptide GHK-Cu is found naturally in the human body, and combines the element copper with three amino acids, making it a tripeptide.

What is it used for?

Copper peptides have antioxidant and anti-inflammatory effects and can promote wound healing, collagen stimulation and attraction of immune cells. The level of tripeptide GHK-Cu naturally occurring in the body reduces with age. In skincare it is mainly used as an anti-ageing ingredient, but is believed to also help with general skin health, including improved skin texture and treatment of scarring. In anti-ageing products it generally appears in lower concentrations of less than one per cent.

What are the pros and cons of using it?

By increasing collagen production, copper tripeptide could improve skin firmness, elasticity and plumpness, whilst its wound-healing properties make it a great treatment for acne scars, wrinkles and marks. However, independent research into copper peptides in skincare is relatively new, so – whilst consumers have fallen in love with its wrinkle-smoothing properties – the scientific benefits when compared to other anti-ageing heroes like retinol have not been proven absolutely.

Which products can I find it in?

Copper peptides are at their best in serums, concentrates and creams which can take their time to work on the skin – as opposed to wash-away products. Three ways to try out copper peptides are Niod Copper Amino Isolate Serum 1.00%, Strivectin Advanced Retinol Intensive Night Moisturiser and Sunday Riley Bionic Anti-Aging Cream.

Read more: Skincare Alphabet: B Is For BHA

Read more: Skincare Alphabet: A Is For AHAs

All products featured on the website are independently selected by our Editors. However, when you buy something through our retail links, we may earn an affiliate commission.

Image: gettyimages

The beauty industry is really coming into the copper peptide products. When I first heard about applying copper for skin improvement, I was shocked. It does not make any sense to me. How a hazardous material like copper can be applied to the skin directly and topically.

I knew that our body has copper in it and the element is needed for various body function making it not only a useful item for the body but a must mineral for proper growth. But, the skincare products with copper peptides can be magic.

After much study, I find out why and how it can be helpful and why it is a must to have for your skin. They use the copper peptide for skin that is small segments of a copper protein that can easily penetrate through the skin and do its magic. It is a remarkable skin regenerator without any harm.

There was a study conducted around the time of 70’s where the Biochemist Loren Pickart discovered that copper peptides could deliver the benefits of the mineral without risk of exposure to hazardous levels of copper.

After that and till now for about 20 years and more copper peptides have been used in various beauty care products and they have brought out remarkable results. You will definitely be amazed to see how wonderfully it works! And today, I will show you 10 best products with copper peptides that you can use for the betterment of your skin.

The best skin care products with copper peptides

1. CopperClear Face Cream

It is a natural and healthy treat for your skin. CopperClear Face Cream helps to reduce blemishes and scars appearing on your skin in just 2 easy steps. Firstly, you have to clean your skin so that oil, junk, dead cells are gone and your pores are clog-free. Then, apply the cream to your skin. You do not have to wash it off. The cream will repair and renew the broken cells as it moisturizes and protects the skin. Be save from red spots and blemishes.

Buy It on Amazon

2. Skin Perfection Copper Peptide Anti-Aging Serum Booster

This product does not use pre-made copper peptides but uses freshly created ones in their lab. Skin Perfection Copper Peptide Anti-Aging Serum gives a boost to your collagen production so that all your wrinkles go away and does not come back anytime soon. Its all-natural peptides regenerate your skin production from its first use. The serum can be used in any homemade product for skincare and also in products for hair. Just add it to your cream, serum, moisturizer, shampoo and apply.

Buy It on Amazon

3. Vernal Skincare Anti Aging Copper Peptides Moisturizer

You can now permanently eliminate the appearance of fine lines and wrinkles by increasing skin tone and elasticity. Vernal Skincare Anti Aging Moisturizer is an anti-aging cream infused with immediate and long-term peptides, vitamin C made to provide structural lift and reduction of wrinkles. The moisturizer boost oxygenation and metabolic performance brightens your skin and produces a natural glow and shine, reduce the appearance of dark circles and puffiness around your eyes and is anti-inflammatory. The moisturizer absorbs in quickly in your skin.

Buy It on Amazon

4. Sotera Skincare Face Serum

The serum works to promote collagen production, reduce fine lines and wrinkles as well as promote skin regeneration. It is the most advanced anti-aging science stored in a convenient bottle. Sotera Skincare Face Serum is an effective at-home remedy for the damaged skin. It heals damages from harsh conditions, laser peels or other forms of skin abrasion. It has plant-based ingredients, safe for all skin types, contains oil-free ingredients of pure vegan origin with a unique blend of copper peptides, coq10, and hyaluronic acid

Buy It on Amazon

5. Face Food NutraNuva Anti Aging Serum

It is infused with Hyaluronic Acid, Peptides, CoQ10, Vitamin C & E, Retinol, phytoceramides, Marine Collagen and so on making it the perfect night and day cream to fighting against the clock, recommended by both dermatologist and plastic surgeons. Face Food NutraNuva Anti Aging Serum nourishes, repairs and renews your skin. It gives you a softer, smoother, younger-looking glowing skin. Wear it with your makeup if want and see 44.9% fewer wrinkles and other age signs within 2 months of use.

Buy It on Amazon

6. Trophy Skin Argan Stem Cell Serum

When you renew your skin with the powerful antioxidant properties of natural argan plant stem cells soothe it as well. Trophy Skin Argan Stem Cell Serum is derived from the stem cells that stimulate the skin’s natural repair process and reverse the signs of aging. It contains hyaluronic acid & copper peptides that protect the skin from environmental factors and targets a deeper skin layer to stimulate the skin’s natural self-repairing process to restore firmness in the skin and promote total cell turnover.

Buy It on Amazon

7. Folligen Therapy Shampoo

The product is formulated by the biochemist Dr. Loren Pickart himself. It is natural, safe and very effective. Folligen Therapy Shampoo prevents hair loss and thinning hair among men and women and promotes new hair growth while the protective copper-peptides and amino acids nourish scalp skin’s health. The shampoo is very mild that cleans your hair and scalp without damaging it. The product re-harden hair proteins, re-seal hair shafts and add protective factors to your hair to enhance its health, beauty, and vitality.

Buy It on Amazon

8. LUXE Beauty Lash & Brow Growth Products Accelerator Eyebrow Enhancing Serum

It is a unique peptide complex formula which ingredients synergistically works to improve the overall appearance of weak, thin and aged eyebrows. LUXE Beauty Lash & Brow Growth Products Accelerator Eyebrow Enhancing Serum is a powerful product and one of the most effective younger-looking brow enhancing solutions. It contains 100% botanical extracts and premium ingredients. It is easy to use, lightweight, leaves no residue and is safe for use on color-treated brows. You can apply it to your makeup also.

Buy It on Amazon

9. JJ Labs Skin Solution Pro Skincare Serum with Copper Peptide and Hyaluronic Acid

This pro skincare serum with copper peptide, hyaluronic acid, allantoin, CoQ-10, aloe vera, green tea, and Echinacea carries five different strengths for different skin types: Vitamin C 10%- for sensitive skin, Vitamin C 15%- for dry skin, Vitamin C 20%- for all skin types, Vitamin C 25%- for oily or mature skin or skin with clogged pores, and High Potency Vitamin C pH 4.5- for the extremely sensitive skin. JJ Labs Pro Skincare Serum will make your skin looking and feeling younger in a matter of days.

Buy It on Amazon

10. Platinum Skin Care Copper Peptide Serum

This scar modeling product is compatible with anti-aging, scar removal, skin remodeling, and acne. The process that removes proteins and older cells from the skin thus it removes scars, lesions, and wrinkles while smoothing the skin is called skin remodeling. Diabetes patients’ wounds will be healed and the scar will be taken care of too with Platinum Skin Care Copper Peptide Serum. The application of peptide-copper complexes to the skin’s surface creates an environment that helps the skin tighten the barrier and increase collagen and elastin density.

Buy It on Amazon


Hope, these products with copper peptides will improve your skin appearance and health. Choose your favorite one from the above list and let us know of your experiences.

With time and new inventions, every day staying young for a long time is no longer a fairy tale subject. In fact, it is a sweet reality (look at all the celebrities) that can be achieved with a bit of care and the right product. So, do not let your youth leave your side. Stay young at both heart and body using good products.

Why Skin-Care Companies Are Using Copper As an Anti-Aging Ingredient


Copper is a trendy skin-care ingredient, but it’s not actually anything new. Ancient Egyptians (including Cleopatra) used the metal to sterilize wounds and drinking water, and the Aztecs gargled with copper to treat sore throats. Fast forward thousands of years and the ingredient is making a major resurgence, with creams, serums, and even fabrics popping up with promising anti-aging results.

Today’s creams feature a natural form of copper called copper tripeptide-1, says Stephen Alain Ko, a Toronto-based cosmetic chemist who has studied copper. Also called copper peptide GHK-Cu, the copper complex was first uncovered in human plasma (but it’s also found in urine and saliva), and is a type of peptide that seeps into skin easily. Many of the newer products use these types of naturally occurring peptides or copper complexes, he adds.

Previous forms of copper were often less concentrated or irritating or unstable. Copper peptides, however, rarely irritate the skin, which makes them a popular ingredient when combined with other so-called cosmeceuticals (cosmetic ingredients said to have medical properties), says Murad Alam, M.D., professor of dermatology at Northwestern University’s Feinberg School of Medicine and a dermatologist at Northwestern Memorial Hospital. “The argument for copper peptides is that they are small molecules important for various body functions, and if they are applied to the skin as topicals, they can enter the skin and improve its functioning,” he explains. This translates to anti-aging perks. “Copper peptides may reduce inflammation and speed up wound healing, which may help the skin look and feel younger and fresher.” (Related: The Best Anti-Aging Night Creams, According to Dermatologists)

Before you stock up, it’s worth noting that there’s no conclusive evidence of its efficacy yet. Studies are often commissioned by the manufacturers or done on a small scale, without peer review. But “there have been a few human studies on copper tripeptide-1 on skin aging, and most of them have found positive effects,” Dr. Alam says. Specifically, a handful of studies showed that copper may make skin more dense and firm, he says.

Dr. Alam recommends trying out a copper peptide for one to three months without changing other parts of your beauty routine. Keeping the other products to a minimum can better help you track skin results to gauge whether “you like what you see,” he says.

Here’s what to try:

1. NIOD Copper Amino Isolate Serum ($60; The scientifically focused beauty brand touts a 1 percent concentration of pure copper tripeptide-1 in its serum and is concentrated enough that you’ll notice real skin changes, the company says. The cult product (which needs to be mixed with an “activator” prior to the first application) has a watery blue texture. Fans say it improves skin texture, decreases redness, and helps diminish fine lines.

2. IT Cosmetics Bye Bye Under Eye ($48; Makers of the eye cream use copper, caffeine, vitamin C, and cucumber extract to create that instantly awake feeling even if you’ve just rolled out of bed. The cream’s blue tint-partially from the copper-helps to minimize dark circles, according to the brand.

3. Aesop Elemental Facial Barrier Cream ($60; The face cream uses copper PCA (a soothing ingredient that uses the copper salt pyrrolidone carboxylic acid) to get rid of redness and promote moisture. The cream can be especially useful when temps start to drop.

4. Iluminage Skin Rejuvenating Pillowcase with Copper Oxide ($60; You may also be able to reap the anti-aging benefits from copper without using a cream or serum with copper peptides. This copper oxide-infused pillowcase helps to reduce the appearance of fine lines and wrinkles by transferring copper ions to the upper layers of your skin while you sleep.

  • By By Alina Dizik

Copper and Your Skin: Facelift In A Bottle

Copper Applications in Health and Environment Area

By William H. Dresher, Ph.D., P.E.

Cosmetics | Copper in Cosmetics | Dr. Loren R. Pickart | Science | Summary | Author | References



A new rage has hit Hollywood — a chemical facelift! Women and men have used cosmetics for thousands of years to enhance the skin; however, it has only been recently that cosmetic products have been available to structurally alter the skin. The ancient Egyptians applied perfumes and anointing oils to their body as early as 4000 BC. The bust of the Egyptian queen, Nefertiti (1367–1350 BC) (the word nefer means beautiful) that stands in the entry of the Berlin Museum is mute testimony to the level of cosmetic art available and used in those early years. Even then, copper was a part of their cosmetics. Eye makeup was probably the most characteristic of the Egyptian cosmetics. The most popular colors were green and black. The green was originally made from malachite, an oxide of copper, and the black, from galena, a lead sulfide mineral.

Copper in Cosmetics

The so-called chemical face-lift products are a range of face creams containing a copper peptide2. They are advertised in many of the major beauty and fitness magazines as “a face lift in a bottle.” Although available to spas, salons and professionals since 1989, copper-peptide products for tissue regeneration were first introduced to the mass market in 1997. Today they are available in local drug stores, department stores, by mail order and over the Internet. They range in price from about $10 to about $75 per oz.

The person whose innovation has made possible the use of copper in skin care products is a biochemist, Dr. Loren R. Pickart, who developed the first such products as a result of his graduate work at the University of California – San Francisco in the1970s. As a result of Dr. Pickart’s work, by 2001, over 40 products based on copper-peptide-induced tissue regeneration are marketed by at least 12 companies throughout the world. In addition, to the so-called face lift products, copper peptides are used:

  • in products that aid skin healing post surgery; after laser resurfacing, dermabrasion and chemical peels;
  • to stimulate hair growth and during the transplantation of hair;
  • to aid skin conditions in persons with acne, diabetes and psoriasis;
  • for use as sun tanning lotion for increasing the efficiency of melanogenesis and reducing post-tanning skin peeling;
  • in after shave lotions; and
  • in veterinary wound cleanser and healing products.

Studies have shown that copper peptide-containing products are more effective than topical application of the more traditional dermatological treatments — Vitamin C, tretinoin or melatonin — on the ultra structure of the skin3.

Some Copper Peptide Products Currently Available on the Mass Market

Company Location Brand Name Products
Ellen Lange Skin Science Highland Park, NJ Ellen Lange™ Peel Plus Pads
DDF Skincare Yonkers, NY DDF™ Cellular Revitalization Age Renewal
Johnson & Johnson Sommerville, NJ Neutrogena™ Visibly Firm Night Cream, Visibly Firm Eye Cream, Visibly Firm Moisture Makeup and Visibly Firm Eye Treatment Concealor
June Jacobs Laboratories New York, NY June Jacobs Spa™ Age Defying Copper Complex
Osmotics Cosmeseuticals Denver, CO Osmotics™ Blue Copper 5 Face Lift Serum, Blue Copper 5 Firming Elasticity Repair, and Male Blue Copper 5 After shave Lotion
PhotoMedex, Inc. Montgomeryville, PA Neova™ Day Theraphy SPF 20, GHK Copper Trio Kit, Eye Therapy, Antioxidant Therapy Serum, Therapy Crème De La Copper, Therapy Dual Action Lotion and After Shave Therapy
Complex Cu™ Post Procedure Skin Care
GraftCyte™ Hair Transplant Care
Tricomin™ Advanced Care for Thinning Hair
Skin Biology, Inc. Bellevue, WA Protect and Restore Classic Cream, Copper Peptide Serum, Folligin Lotion, Folligin Therapy Shampoo and Bioheal
Sothys Paris, France Sothys Paris™ Hydra-Protective Cream

Dr. Loren R. Pickart

While a graduate student at the University of California – San Francisco in the 1970s, Dr. Pickart studied the biochemistry of human aging. Scientists had isolated a sequence of amino acids (glycyl-L-histadyl-L-lysine, a peptide) in human serum that bound copper. In 1973, Pickart found copper glycyl-L-histadyl-L-lysine (GHL-Cu) to be abundant in young people but diminished in older people. He reasoned and later proved that GHL-Cu is the agent that stimulates tissue regeneration; namely, skin regeneration and remodeling, increase in collagen and elastin, rebuilding of blood microcirculation and increase in subcutaneous fat cells4, 5, 6, 7. He later named the GHL-Cu factor Iamin (from the classical Greek word “iama” or curative substance). Later research indicated that Iamin is generated during tissue damage and suggests that the build up of Iamin in the area of tissue damage causes an influx of skin repair cells called acrophages that initiate skin repair mechanisms. He reasoned that the decrease in the blood concentrations of Iamin with aging might be a major cause of the decreased tissue regeneration and organ failure that occurs during the human aging process.

Subsequent work over the next ten years established the chemical and physical structure of the copper complex. By 1983, there were the first laboratory indications that GHL-Cu was a type of metabolically active copper that functioned as a trigger of wound healing and tissue regeneration. Dr. Pickart applied for and has received numerous patents in the USA and in various foreign countries in the areas of: skin regeneration and safer sun tanning; treatment of aging skin, hair regrowth and hair loss prevention, wound healing (chronic skin ulcers, surgical wounds, burns), treatment for inflammatory bowel disease, prevention and healing of stomach ulcers, bone repair, and blockage of reperfusion8 injury and improvement of fingernail and toenail growth and strength.

In 1985, Pickart formed ProCyte Corporation (ProCyte means “for the cell’) for the specific purpose of developing and marketing wound healing and hair restoration products based on his copper peptide technology. The company went public (OTCBB –PRCY) in 1989 to market products for hair growth and loss prevention and for wound healing. Pickart subsequently left the company in 1991 for health reasons.

In 1992, Pickart formed a second, privately owned, company, Skin Biology, Inc.9 to focus on skin care products. The basis of the new company is a second line of copper peptides based on soy bean-derived peptones10. According to Pickart, whereas the natural GHL – Cu peptide has the problem of being very fragile, breaking down rapidly and short acting, and cannot be used in combination with hydroxy acids, this second generation of copper peptides is very stable, is breakdown-resistant and can be used concurrently with hydroxy acids. According to the company, these compounds have been demonstrated to have strong skin repair and anti-inflammatory properties. Skin Biology products are sold by mail order or over the Internet11.

In the meantime, in July 1999, ProCyte acquired Nextderm, Inc., to round out its product line with dermatology and skin care products. It also became a contract manufacturer of various drugs for pharmaceutical companies. In 2000, ProCyte licensed its copper peptide technology to Johnson & Johnson’s Neutrogena™ unit for worldwide use in products involving skin health. In 2001, ProCyte announced a long-term license and supply agreements with American Crew, a leading salon hair care and beauty supply company, for use of its patented AHK Copper Peptide Complex for hair care products for sale in the hair and beauty salon and day spa marketplaces. Since that time, they have added licensees: AdvoCare, Amuchina (Europe), Atelier Esthetique, Bard Medical, BioPharm (Middle East), Creative Nail Design, Schering AG, Osmotics, Sigmacon Medical Products (Canada) and Tanox Biosystems (Asia).

In March 2005, ProCyte merged with PhotoMedex, Inc.12, and operates as a division of that company.

Science Behind Copper Peptide Cosmetic Products

Copper’s role in skin care and wound treatment was first discussed in the Ebers Papyrus — the oldest book known to man and written in approximately 1550 BC13. The Ebers Papyrus documents folk medicine practiced in ancient Egypt at the time of its writing and many centuries earlier. Specifically, the treatment of burn wounds and certain growths of the neck (presumably boils) are mentioned, as are remedies for eye ailments. Subsequent medical volumes — the Hippocratic Collection (460 to 380 BC), De Medicina (14–37 AD), Pliney’s Historia Naturalis (23–79 AD) — copper compounds are called for in the treatment of various skin diseases and infections.

Although ancient practice and basic science had paved the way for medicinal use in wound healing, it was not until recently that consideration was given to the use of copper in cosmetic preparations. It has long been known that copper combines with certain proteins in the body to produce enzymes that act as catalysts assisting a number of body functions. Some of these enzymes help provide energy required by biochemical reactions; others are involved in the transformation of melanin for pigmentation of the skin; and still others help to form cross-links in collagen and elastin and thereby maintain and repair connective tissues. It has also been known that copper complexes can be used to both prevent and to repair injury to tissue due to ionizing radiation14.

Recently, scientists in France have found that GHL-Cu stimulates collagen synthesis15. At Stanford University’s Wound Healing and Tissue Engineering Laboratory, scientists have found that certain types of copper peptides help the process of skin remodeling and removal of scar tissue16. Such types of copper peptides help activate the skin’s metalloproteinases that remove damage proteins (sun as sun-damaged collagen and elastin) and scars. At the same time, they help activate the your skin’s anti-proteinases TIMP-1 andTIMP-2, which protect against excessive breakdown of protein17. Thus, copper peptides added to skin creams help the process of rebuilding new collagen and elastin into the skin.

According to Pickart, numerous research and human clinical studies at over thirty universities and medical research institutes have found copper-peptides in animal and human studies to:

  • Accelerate wound repair (humans, mice, rats, guinea pigs, pigs, dogs)
  • Increases skin re-epithelialization (humans and animals)18.
  • Reverses aging effects on skin (humans) — thickens skin, improves elasticity, and increases subcutaneous fat layer • Improve skin graft transplant success (pigs)
  • Improve hair transplant success (humans)
  • GHL analogs with fatty residue analogs increase hair follicle size and growth rate
  • Stimulate hair growth and reduce hair loss (humans, mice, rats)
  • Stimulate bone healing (guinea pigs, pigs, rabbits)
  • Heal injured intestinal linings (humans, rats)
  • Heal stomach ulcers (rats)
  • Blocks oxidative injury in tissues


It has been found that biologically effective copper-peptides help the skin to:

  • Regenerate new collagen and elastin which improves skin firmness and elasticity,
  • Increase the production of water-holding glycosaminoglycans which is true moisturization,
  • Improve the skin’s blood vessel microcirculation,
  • Produce biochemical energy from nutrients in the body’s blood supply,
  • Increase the natural defense mechanism against oxidative damage, and
  • Repair damage to the protective skin barrier. As the skin is rebuilt and scars removed, the elastic properties of the skin pull it into a smooth surface.

Thus, in addition to copper being an essential element of life19, copper is equally important in staving off the ravages of time to our appearance and in the maintenance of the elusive physiological quality we call beauty.

Author Information

William H. Dresher has over 30 years experience in corporate and academic management in R&D, in the fields of extractive metallurgy of base and refractory metals, copper processing, products and marketing, as well as expertise in the environmental aspects of copper in health and ecotoxicity. In his career he has been Assistant Director of Research for Union Carbide Corporation’s Mining and Metals Division, Dean of the College of Mines of the University of Arizona, President of the International Copper Research Association, Inc. and most recently, the Vice President of Technology of the International Copper Association, Ltd. He is a graduate of Drexel University in Philadelphia with a BS degree in Chemical Engineering and of the University of Utah with a Ph.D. in Metallurgy.

1. Cosmetics are defined as substances applied to the body to cleanse, promote attractiveness, or alter the appearance. They include underarm deodorants, face powder, lipstick, nail polish, perfume, skin cream, most shampoos, hair conditioners, dyes and bleaches, some toothpastes and, now, creams and lotions that alter the condition of the skin.

2. A peptide is any of various natural or synthetic compounds containing two or more amino acids linked by the carboxyl group of one amino acid and the amino group of another.

5. Pickart, L.R., “The use of glyclhistidyllysine in culture systems,” In Vitro, Vol 17, No. 6, 1981, pp 459 – 466.

8. Reperfusion -tissue injury after stoppage of blood flow.

9. Skin Biology, Inc. 12833 SE 40th Place, Bellevue, WA 98006.

10. A peptone is any of various compounds obtained by acid or enzyme hydrolysis of natural protein and used as nutrients in culture media in bacteriology.

11. Please visit for additional information.

12. PhotoMedex, Inc., 147 Keystone Drive, Montgomeryville, PA 18936.

17. Simeon, C.P., Y. Wegrowski, P. Bontemps and F.X Marquart, J Invest Dermatol Vol 115, No.6, 2000, pp 962-968.

18. The epithelium is membranous tissue composed of one or more layers of cells separated by very little intercellular substance and forming the covering of most internal and external surfaces of the body and its organs.

19. Environment and Health section of Copper In Your Home.

Also in this Issue:

  • Copper and Your Skin: Facelift In A Bottle

What Are The Best Products With Copper Peptides?

I’m jumping on the copper peptides bandwagon.

I admit I was hesitant at first. Research was scant and the prices outrageous. I’m not gonna shell out 100+ for something I’m not even sure works.

But in the past year, resisting the temptation was harder and harder. For one, new studies are coming out proving that copper peptides DO something for your skin.

Plus, prices are going down (and if that’s not the way to a girl’s skincare cabinet, I don’t know what is). So I’m giving them the Beautiful with Brains stamp of approval.

The only question now is: what are the best products with copper peptides? But first, let’s rewind things a little and find out what exactly it is they do for your skin:

What The Heck Are Copper Peptides?

Peptides are proteins made up of amino acids (the building blocks of skin). Some of these peptides have an affinity for the metal copper. When they meet, they become one: a copper peptide. Duh!

It’s a match made in skincare heaven. Why? Copper peptides help your skin in so many ways:

  • They boost collagen: they can increase the production of collagen, the substance that keeps skin firm. Rumour has it, they do this better than vitamins A & C!
  • They heal skin: they soothe irritations and help wounds heal faster.
  • They produce antioxidant enzymes: for example, superoxide dismutase, which destroys the worst, most damaging type of free radical in your skin.
  • They strengthen the skin’s protective barrier: they promote the production of elastin, glycosaminoglycans, proteoglycans, and other building blocks of the barrier.

Pretty impressive, aren’t they?

Related: Are Copper Peptides Better Than Retinoids?

Before I tell you what the best products with copper peptides are, let me get one thing straight: I don’t think these peptides are a must for everyone. Most of you won’t need them. For now.

But if your skin is losing firmness, frequently acts up or you want to minimise retinoid irritation, adding copper peptides to your skincare routine can help.

But where to find them? Here are the best products with copper peptides (that don’t break the bank – this stuff can cost a pretty penny!):

Best For Dry Skin: Drunk Elephant Protini Polypeptide Cream ($68.00)

The name says it all: Drunk Elephant Protini Polypeptide Cream has every peptide you can think of. They work by signalling skin cells how to behave. Some of these peptides tell skin to produce more collagen, others to amp up its hydration levels, others still to heal and soothe skin… You get the drill. The addition of marula oil makes it more suitable for dry skin but every skin type can use it.

Available at: Cult Beauty,Sephora and SpaceNK

Related: Do Peptides In Skincare Really Work?

Best For Mature Skin: Niod Copper Amino Isolate Serum 2:1 (£38.00)

Niod Copper Amino Isolate Serum 2:1 was the product that converted me to copper peptides (ok, the first version but the upgraded one is even better). It has one of the highest concentration of copper peptides I’ve seen in a skincare product – and not much else. It works by keeping skin in a constant state of repair, making sure that everything’s functioning properly. If you’re young and blessed with good skin, you’ll think it’s not doing anything for you. But if you’re a little older and need the extra help, you’ll notice your skin getting firmer, more tolerant of prescription retinoids (& other “harsh” ingredients) and healing much faster.

Available at: Cult Beauty and Net-A-Porter

Related: My Full Review Of Niod Copper Amino Isolate Serum 2:1

Best On A Budget: The Ordinary Buffet + Copper Peptides 1% ($28.90)

The Ordinary Buffet + Copper Peptides 1% is pricer than your average The Ordinary products. But it’s still your best bet if you want to see what the fuss is about without committing too much money. Plus, it has 5 more peptide complexes, including Matrixyl 3000 to boost collagen and SYN-AKE to freeze muscle movements (it was inspired by the paralysing effect of snake venom). No, it doesn’t work as well as Botox but hey, every little bit helps.

Available: Asos, Beauty Bay, Cult Beauty and Look Fantastic

Related: What Type Of Peptides Works Best To Repair Skin?

Best For The Eye Area: Drunk Elephant Shaba Complex Eye Serum ($85.00)

I know, I know. I always say you don’t need an eye cream. I 100% stand by that. But I know a lot of you like to use one anyway. That’s totally cool. Your face, your choice. So, if you’re looking for one with copper peptides, go with Drunk Elephant Shaba Complex Eye Serum. It’s expensive, but well worth the money. It’s a cocktail of peptides (NOT just copper peptides), antioxidant and niacinamide that moisturises skin, fights wrinkles and soothes irritations.

Available at: Drunk Elephant

Related: Niacinamide, A Skincare Do-It-All


It’s your turn! What are, in your opinion, the best products with copper peptides? Share your thoughts in the comments below.

Take The Guesswork Out Of Skincare Shopping

Get access to the “Pro Skincare Library” for exclusive skincare routine “cheat sheets” and tricks to help you navigate the beauty aisles jungle like a pro and immediately know what to pick off the shelves to achieve the gorgeous skin of your dreams – even when you’re drowning in an endless sea of skincare products.

All Copper ‘Errything – 10 Impressive Health Benefits of Copper

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Copper has been used for construction since prehistoric times, even before recorded history. Ancient civilizations even utilized the compounds in metals such as copper, zinc and manganese in their medicines and treatments. And as it turns out, copper has a wide range of health benefits!
Copper is an essential micronutrient that has numerous health, wellness and beauty benefits, from improved appearance of skin, to treatment of wounds and skin conditions, and also aids in maintaining metabolic processes, among countless other health benefits.
Your body does not produce copper naturally, so you must add it to your body from external sources. Copper is found in many foods that you eat, including beans, nuts and seeds, seafood such as oysters, leafy greens, whole grains, soy, beets, avocados and cocoa.
Your body stores copper in your bones and muscles. You can also introduce copper to your body by drinking water from copper vessels or wearing copper jewelry.

Here Are 10 Compelling Health Benefits of Copper:

1. Anti-Aging

Copper is an antioxidant that can improve the condition of your skin. It safeguards your cell membranes from free radicals and helps your skin and joints produce collagen and elastin to prevent premature aging and promote skin elasticity. Even the Egyptian gods Cleopatra and Nefertiti used copper to stay youthful.

2. Skin Health

Copper is a component of melanin, which provides pigment and sun protection to your hair, skin and eyes. It also aids in the production of new cells, replenishing the top layer of your skin to produce a smooth and clear appearance.

3. Antibacterial

Copper destroys and inhibits the growth of microbes, fungi and bacteria, including E Coli. It can be used as medicine when ingested (from water stored in a copper vessel) or applied topically to boost your immune system, prevent infection, improve wound healing and speed the healing process of tissues. In fact, the U.S. EPA found copper to be the only solid material that can kill bacteria that pose a threat to human health.

4. Cognitive Stimulant

Copper is a brain stimulant that is associated with higher thought processes. Copper opens neural pathways and encourages creativity and improved brain functioning. In short, it makes your brain work faster and more efficiently – who doesn’t want that?!

5. Anti-Inflammatory

Naturally anti-inflammatory, copper can be used to provide relief from aches and pains caused by arthritis or inflamed joints. It also has bone and immune system strengthening properties.

6. Prevent Bone Loss

It can also slow down bone loss and osteoporosis in older women when taken in conjunction with other key vitamins including zinc, calcium and manganese. Copper has bone-strengthening properties and its collagen-forming qualities encourage strong bones and connective tissues.

5. Reduces Cholesterol

Copper can reduce LDL cholesterol (the bad kind) and triglyceride levels, and increase HDL cholesterol (the good kind). Having more good than bad cholesterol can reduce your risk of developing cardiovascular disease, heart attacks, and strokes.

6. Good Circulation

Copper helps your body absorb iron (from food and other sources in your intestines) and release it as needed to essential organs like the liver. Copper regulates blood flow and improves your circulation by maintaining iron levels in your blood. This aids your body in maintaining a healthy red blood cell count and adequate oxidation in your internal organs.

7. Improve Digestion

Copper is an essential trace element that is great for your digestive system and metabolism. It can aid in the digestion of food, kill harmful bacteria that might be present in your water, and reduce inflammation in your stomach.

8. Weight Loss

Adding copper to your diet can help you lose weight. Copper helps fine-tune your digestive system, break down fats, and helps you to eliminate more efficiently.

9. Anti-Cancer

According to the American Cancer Society, copper has considerable anti-cancer effects. Copper has antioxidant properties that fight off free radicals, which are a cause of cancer.

10. Balance the Doshas

Water that has been stored in a copper vessel is positively charged and full of natural antioxidants. This helps to balance the three doshas in your body: kapha, vata and pitta.

How to Get More Copper in Your Life

There are a variety of ways to integrate copper into your life and diet, including taking supplements, wearing jewelry and copper-infused clothing, and using copper utensils and drinkware. If you would rather utilize the benefits of copper in its non-pill form, jewelry, copper-rich foods and beverage products are a great way to obtain those trace copper elements.
Here’s to your health!

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Copper: The Health Benefits, Deficiency Symptoms, And Side Effects Ravi Teja Tadimalla Hyderabd040-395603080 August 13, 2019

What if I tell you that there is one trace mineral that can boost your brain health and put all brain ailments at bay? Or how about enhancing your immunity big time? I am talking about copper. Though not discussed much, this mineral makes your life better in several ways. And in this post, we’ll look at all of them – the benefits of copper you must know. Just keep reading.

Table Of Contents

What’s Up With Copper?
What Are The Health Benefits Of Copper?
What Are The Signs Of Copper Deficiency?
What Are The Foods Rich In Copper?
What Are The Side Effects Of Excess Copper?

What’s Up With Copper?

There are quite a number of ways copper can benefit you. The first of them is it provides energy to the brain and improves the functioning of the nervous system. It also helps in the production of red blood cells – it aids the process and boosts your immunity. It achieves this along with iron.

Copper also contributes to the health of bones, nerves, and even promotes iron absorption (offering an entirely different set of benefits) in a way.

Well, there’s more. Why don’t you just check them out?

Back To TOC

What Are The Health Benefits Of Copper?

1. Boosts Your Brain Health

Copper is one important ingredient of enzymes that activate the brain’s neurotransmitters. New research indicates that adequate copper levels are essential to brain health. The brain takes in 20 percent of the oxygen you inhale. And since most copper in the body is found in the brain, the organ sure needs adequate copper (1).

Neurodegeneration in adults is often linked to an imbalance in copper levels. Also, a couple of the symptoms of copper deficiency are the inability to concentrate and poor mood.

2. Boosts Your Joint And Bone Health

Copper contributes to bone mineral density, and low levels of the mineral can lead to osteoporosis (2). It also plays a role in collagen health, which is an important structural component in our bodies. Insufficient copper can lead to depletion of collagen, and this eventually results in joint dysfunction.

The anti-inflammatory properties of copper can also ease arthritis pain.

And, by the way, there are some claims going on about copper bracelets and how they can treat joint pains. Proponents claim that the anti-inflammatory properties of the copper in the bracelet can get transferred to the body upon contact. Let me tell you that there is no research to support this claim (3).

3. Strengthens Your Immunity

As we discussed earlier, copper, along with iron, helps in the production of red blood cells. This builds your immunity. Deficiency in copper can lead to neutropenia, which is a lower amount of white blood cells – and research says this condition can cause one to fall ill more often. These effects are more pronounced in infants, which is why they need to have sufficient copper levels more than anyone else (4).

4. Promotes Metabolism

Copper supports over 50 enzymatic reactions that take place in your body on a daily basis. This supports a healthy metabolism.

The mineral also plays a role in the synthesis of ATP, or adenosine triphosphate – which is the body’s source of energy. Which is why deficiency of copper can lead to a sluggish metabolism.

5. Contributes To Proper Growth And Development

Copper deficiency, unfortunately, is quite common in third world countries and is quite visible in children – where kids suffer from stunted growth and other developmental complications. This is because copper deficiency can affect joint and bone development and even the development of the brain.

Additionally, copper is also required for the oxygenation of red blood cells – and low levels of the mineral can mean your organs do not receive adequate levels of oxygen. This can lead to developmental issues. Studies show that deficiency in copper can also delay growth in infants.

6. Supports Your Thyroid Health

Copper works with potassium, zinc, calcium, and potassium (essential nutrients for thyroid health) and promotes thyroid health. As a result, it can help prevent conditions like hypothyroidism or hyperthyroidism.

Studies suggest that how the metabolism of copper is essential to prevent or manage thyroid disease (5).

7. Delays Aging

Studies show that copper is as important to anti-aging as retinol and alpha hydroxy acids. And then, there are copper peptides, a copper complex that can reduce inflammation and keep the skin looking younger and fresher. Since copper helps build collagen, and since collagen is also important to maintain skin elasticity, it should be safe to say that copper can improve skin firmness and reduce wrinkles.

Studies also state that copper stabilizes skin proteins, improving the overall skin health (6). It also helps in the production of melanin, which is the pigment that protects your skin from UV radiation.

8. Copper Can Boost Your Hair Health

Copper peptides are also known to increase the size of the hair follicles and subsequently stop hair thinning. And since copper helps in the production of melanin, it can even prevent premature graying of hair.

These are the benefits of copper. These tell us how important the trace mineral is, don’t they? Inadequate levels of this mineral can lead to complications. Let’s see what they are.

Back To TOC

What Are The Signs Of Copper Deficiency?

Deficiency of copper can lead to the following issues:

  • Anemia
  • Bone fractures
  • Thyroid issues
  • Osteoporosis
  • Loss of pigmentation of hair and skin
  • Menkes disease (neurodevelopmental delays in infants)

The only way to prevent copper deficiency is by ensuring you take enough it. Which takes us to the next section.

Back To TOC

What Are The Foods Rich In Copper?

The RDA of copper is 900 mcg a day for both adults and adolescents. And the upper limit is 10 mg per day. Keeping that in mind, you can include the following foods in your diet as required:

All good. But do you know that excess copper in your body can cause issues?

Back To TOC

What Are The Side Effects Of Excess Copper?

  • Issues During Pregnancy And Breastfeeding

Taking copper in higher doses during pregnancy and breastfeeding can be unsafe. Pregnant women above 19 years of age must take no more than 10 mg of copper a day.

  • Wilson’s Disease

Excess copper levels in the body can lead to copper toxicity, which can affect the major organs of the body.

  • Other Side Effects

Headache, dizziness, weakness, liver cirrhosis, and jaundice.

  • Drug Interactions

Excess copper, especially in the supplemental form, can interact with birth control pills, NSAIDs like aspirin and ibuprofen, penicillamine, allopurinol, and other zinc supplements.

Back To TOC


It could be a trace mineral, but it sure does benefit you in several ways, doesn’t it? So, why don’t you start by including more of the foods rich in copper?

And why don’t you leave a comment below? Let us know how this post has helped you.

1. “Copper on the brain at rest”. ScienceDaily.
2. “Mechanisms for copper acquisition…”. US National Library of Medicine.
3. “Copper bracelets and magnetic wrist…”. US National Library of Medicine.
4. “Copper”. Oregon State University.
5. “Zinc, copper, manganese…”. US National Library of Medicine.
6. “Using copper to improve the…”. US National Library of Medicine.

Recommended Articles:

  • Reasons Why You Should Drink Water From A Copper Pot
  • Best Benefits Of Magnesium For Skin, Hair, And Health
  • 10 Best Health Benefits Of Calcium
  • 12 Amazing Health Benefits Of Manganese

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Ravi Teja Tadimalla

Ravi Teja Tadimalla is a Senior Content Writer who specializes in writing on Health and Wellness. He graduated from SRM University, Chennai, and has been in the field for well over 4 years now. His work involves extensive research on how one can maintain better health through natural foods and organic supplements. Ravi has written over 250 articles and is also a published author. Reading and theater are his other interests.

Here’s What Copper Jewelry Is Telling You When Your Skin Turns Green

Copper could easily be considered one of the world’s most popular metals. An essential mineral since ancient times, one of the major “ages” of humanity is named after a copper alloy- namely, bronze. Copper and its many alloys have played an essential role in many civilizations: from the Egyptians to the Romans, Greeks, and even all the modern day cultures use copper in a nearly limitless capacity. Without a doubt, utilizing copper is one of the most important technologies ever developed by humanity!

SEE ALSO: The Top 5 Benefits Of Copper

From the big to the little

Copper was highly prized for its use in creating weapons and tools, but over time it also began to be used for something unexpected. Royalty is always interested in the rarest and hardest-to-find materials, so it makes sense that they’d be interested in pure copper’s unique properties.

This eventually developed into a love for copper plates, cups, furnishings, and jewelry.

As this obsession with jewelry and unique metals deepened, it eventually became widely known that copper had some uncommon healing abilities.

The healing benefits of wearing copper

Wearing copper has several important benefits: First, copper is an essential mineral for humans, and wearing copper jewelry has the benefit of slow copper absorption- perfect for proper assimilation. It’s also been claimed that headaches, arthritis, joint pain, and other deficiencies can be effectively treated with the aid of copper or brass jewelry.

Of course, there is some conflict with these claims, but I have experienced joint relief myself from using copper jewelry. It really worked for me, and lots of other people.

Why does copper turn your skin green?

So if copper is considered healing and has been used for so long in human history, why is it that people have learned to live with green skin? After all, wearing something like a copper bracelet or anything else that’s in close contact with the skin sometimes produces a greenish hue- which is kinda strange, right?

Actually, it’s totally normal.

Copper reacts naturally with our salty skin, which can be created whenever we sweat. This just means you have to be aware of when you might be working out or in the sun. But copper can also react to acidic environments- and your body acidity is related to your diet. Junk food, processed food, and lots of red meat will make your body acidic.

The more acidic your diet and body, the more likely you are to get sick.

This can make copper jewelry a terrific way to gauge whether or not you need to change your diet or if you’re just on the cusp of coming down with something. It can be very useful!

Gorgeous Copper Jewelry You’ll Fall in Love With

Our copper collection is unlike anything you’ve seen before!

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