Is Bee Venom Good For Your Skin? You May Want Add It Into Your Beauty Routine

You may have tried every new beauty/skincare trend out there in the name of taking care of your complexion in hopes of amazing results, but there’s a product you may not have ever thought your skincare routine was missing. If you’ve heard the buzz about it (pun totally intended) and are wondering if bee venom is good for your skin, it absolutely is, and as painful as it sounds, it’s a product you are probably going to want to start using.

As someone who is deathly afraid of bees, the last thing I’d ever want to do is put their venom on my face. I mean, ouch! But it’s not painful, and it’s actually great for your skin. Bee venom is anaphylactic, so it can temporarily relax your facial muscles (natural botox, anyone?), break down cell membranes, and improve circulation, which can create a tighter and smoother complexion. It can also plump out and firm your skin, reducing the appearance of fine lines and wrinkles. So the name might sound painful, but it doesn’t actually sting — and you know a botox needle would!

If you want to give yourself a natural plump and firm your complexion, try these products with bee venom in them.

1. Miss Spa

Miss Spa Bee Venom Plumping & Firming Silk Sheet Mask, $8, Ulta

In addition to the bee venom, this mask has honey extract and aloe to nourish and moisturize.

2. Nip + Fab

Nip + Fab, $32, Asos

This hydrating anti-aging cream will plump your skin and reduce wrinkles.

3. WEI

WEI Bee Venom Anti Wrinkly Mask, $60, Skincare Rx

This gentle and nourishing mask will help correct skin imperfections.

4. Mizon

Bee Venom Face Cream, $29, Beauty Spin

Swap out your standard moisturizer with this cream formulated with bee venom.

5. Rodial Day Cream

Bee Venom Day Cream, $155, Saks Fifth Avenue

Apply this in the morning and your skin will be plumped all day.

6. Rodial Body Souffle

Rodial, $190, Amazon

It isn’t just for your face — bee venom can be used on your body, too.

7. Rodial Serum

Bee Venom Serum, $200, Dermstore

If you want to keep your standard moisturizer, you can apply a bee venum serum first.

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Images: FarFetch, Saks,, Beauty Spin, ULTA, ASOS, Birchbox, Fototalia

Bee Venom: Uses, Benefits, and Side Effects

While not all of the purported benefits of bee venom are backed by science, research has shown that it has several powerful medicinal properties.

Has anti-inflammatory properties

One of the most well-documented benefits of bee venom is its powerful anti-inflammatory effects. Many of its components have been shown to reduce inflammation, particularly melittin — its main component.

Although melittin can cause itching, pain, and inflammation when delivered in high doses, it has potent anti-inflammatory effects when used in small amounts (10).

Melittin has been shown to suppress inflammatory pathways and reduce inflammatory markers, such as tumor necrosis factor alpha (TNF-α) and interleukin 1 beta (IL-1β) (10, 11).

May reduce arthritis-related symptoms

The anti-inflammatory effects of bee venom have been shown to especially benefit those with rheumatoid arthritis (RA), a painful inflammatory condition that affects your joints.

An 8-week study in 120 people with RA found that bee-venom acupuncture, which employed 5–15 bee stings every other day, provided symptom relief effects that were similar to those of traditional RA medications like Methotrexate and Celecoxib (12).

Another study in 100 people with RA showed that combining bee-sting therapy with traditional medications like Methotrexate, Sulfasalazine, and Meloxicam was more effective at reducing pain and joint swelling than treatment with the traditional medication alone (13).

Though promising, more high-quality studies are needed to confirm these effects (14).

May benefit skin health

Multiple skincare companies have started adding bee venom to products like serums and moisturizers. This ingredient may promote skin health in several ways, including by reducing inflammation, providing antibacterial effects, and reducing wrinkles.

A 12-week study in 22 women demonstrated that applying a facial serum containing bee venom twice daily significantly reduced wrinkle depth and total wrinkle count, compared with the placebo (15).

Another 6-week study found that 77% of participants with mild to moderate acne who used a serum containing purified bee venom twice daily experienced an improvement in acne, compared with the placebo (16).

What’s more, test-tube studies have shown that the venom has powerful antibacterial and anti-inflammatory effects against the acne-causing bacteria Propionibacterium acnes (17, 18).

May benefit immune health

Bee venom has been shown to have beneficial effects on immune cells that mediate allergic and inflammatory responses.

Evidence from animal studies suggests that bee-venom therapy might help reduce symptoms of autoimmune conditions, such as lupus, encephalomyelitis, and rheumatoid arthritis, by decreasing inflammation and bolstering your immune response (19, 20).

Other animal studies suggest that bee-venom therapy may also help treat allergic conditions like asthma (21, 22).

It’s thought that bee venom increases the production of regulatory T cells, or Tregs, which inhibit allergen responses and reduce inflammation. Although promising, the effects of bee-venom therapy in humans with allergies is unknown (22, 23).

Additionally, venom immunotherapy, in which bee venom is administered by a healthcare professional by injection — is used to treat people with severe allergies to bee stings.

Research has shown that this treatment is safe and effective and can reduce the future risk of serious reactions to bee stings. In fact, it’s recommended as a first-line treatment for those who are allergic to the venom (24).

Other potential benefits

Though research is limited, bee venom may benefit the following conditions.

  • Neurological diseases. Some research suggests that bee-venom therapy may help reduce symptoms related to neurological diseases, including Parkinson’s disease, though human studies are limited (25).
  • Pain. One study showed that bee-venom acupuncture, along with traditional medication, significantly reduced pain and improved functional status in 54 patients with chronic lower back pain, compared with the placebo group (26).
  • May fight Lyme disease. Some research suggests that bee venom and isolated melittin may have antimicrobial effects against Borrelia burgdorferi, which is the bacteria that causes Lyme disease. However, more research is needed (27).

Although these potential benefits are promising, more research is needed to confirm them.

Summary Bee venom has powerful anti-inflammatory properties and may benefit the health of your skin and immune system. It may also improve certain medical conditions like rheumatoid arthritis and chronic pain.

Is Putting Bee Venom On Your Face As Good As Botox?

Even though weird and wild skincare ingredients have become standard when it comes to beauty, the idea of slathering bee venom on your face still sounds, well, scary.

But with Botox now our most common cosmetic procedure, this natural ingredient (which first made a buzz when it was named as Gwyneth Paltrow and Kate Middleton’s facial of choice) is now considered the gold standard in natural alternatives to tackling fine lines – sans needles.

Why? Because of its ability to deeply penetrate the skin and instantly make it appear lifted, plumper, and firmer.

Botox (which is often injected into forehead lines, crow’s feet and frown lines) works to remove wrinkles by temporarily paralysing the muscle, causing them to relax and soften. It is effective, albeit not everyone is comfortable with injections – or the price point.

However, luckily there are topical substitutes popping up for a fraction of the price (and zero pain.) Enter: skinChemists Advanced Bee Venom Facial Serum, $52.80, which harnesses the plumping benefits of bee venom to reduce visible wrinkles and soften the skin.

So how exactly does it work? The venom itself increases blood circulation, gently plumping out and firming the skin, filling and smoothing fine lines and wrinkles. It also adds a rush of blood to the area and stimulates the production of collagen.

“Just like your usual serum, apply this one morning and night to clean, dry skin. You can put some moisturiser over the top for an extra hit of hydration,” explains senior beauty therapist at, Jade Dowling.

And with Botox costing between $100 to $300 to treat the forehead, if you’re after something more gradual to try out first, then a bee venom serum could very well be your answer.

What your face says about you

What your face says about you

Ashleigh Austen is’s lifestyle editor and writes about everything from way-out wellness trends and workouts to genius beauty hacks and bang-on fashion buys. Fuelled by soy cappuccinos and carrots, she can quote nearly every episode from The Simpsons. Follow her for non-stop serious journalism (lol) on Instagram and Twitter.

Snake Venom Cream – Skincare Snake Active

Skincare Snake Active Snake Venom Cream description

The Skincare Snake Active Cream is a nourishing anti-aging treatment that helps to keep skin looking healthy and youthful. It contains snake venom and a variety of powerful natural ingredients that work in harmony to tackle different skin issues.
Snake venom is known for its lifting effect, as it freezes wrinkles and expression lines. It contains hyaluronic acid and amino acids which contribute to skin looking plumped, healed, and hydrated, with improved elasticity. It also contains elastin, retinol and tocopherol. It also tackles pigmentation issues and sunspots due to its lightening properties.
This soothing face cream revitalizes dry skin, as it contains olive, corn, and wild rose oils. It helps with dry patches and dehydration issues, so that skin has a more uniform appearance and a softer, smoother texture.
This cream has a delicate fragrance and a non-greasy texture, so it doesn’t leave a heavy film on the skin.


50 ml / 1.7 oz

Composition of the Snake Active cream anti-aging

Here’s a good TIL: Snake venom and Botox aren’t all that different. Because venom is a snake’s natural form of defense, it contains neurotoxins that paralyze victims by impacting their neuromuscular function. Botox, of course, also influences the neuromuscular system, preventing it from contracting and causing wrinkles.

In short then, for the skincare-obsessed at least, snake venom is more dream than nightmare. Which is the thinking behind Syn-Ake, a synthetic ingredient mimicking snake venom that’s being used in anti-aging skincare. It was developed by Pentapharm, the pharmaceutical research company in Switzerland whose motto is “Turning nature into life-saving solutions” and who claims that Syn-Ake is a “small peptide that mimics the activity of Waglerin 1, a polypeptide that’s found in the venom of the Temple Viper.” (More on the Temple Viper here.) Pentapharm further promises, “Syn-Ake has been developed as efficient smoothing and anti-wrinkle care particularly effective against expression lines by relaxing facial muscles.”

“To get a real Age Killing Effect, try SYN-AKE,” one Pentapharm campaign reads.

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Snake Booster Oil: Products you’ve never seen for results you’ve never seen. A concentrated, hydrating facial oil to dramatically firm and tighten skin on a long term basis. Anti-inflammatory, anti-oxidant properties, leaves no oiliness on skin. #Rodial

A post shared by Rodial (@rodialbeauty) on Feb 4, 2019 at 8:08am PST

“I definitely thought this was actually snake poison when I first heard about venom products,” says esthetician and product-formulation expert Andrea Amez. “I also initially assumed it was a marketing venture more than anything else. But in the realm of anti-aging, this is basically the next best thing to Botox. Honestly, it’s sort of genius to mime an ingredient that enables muscle paralysis.”

I hate when a skincare product tells me to use it after cleansing but before moisturizing. I’m like duh obviously but do I use it before applying my snake venom or after I mist with my virgin blood

— Lorena Cupcake 🇲🇽 they / them (@lorenacupcake) June 18, 2019

kpop idols: ya i don’t really have a skincare routine i go to the dermatologist and get injected with snake venom and baby placenta every monday but my stans on twitter always paid for it other than that i just eat a lot of dairy and use cetaphil <3

— 💵 (@taedoriya) May 17, 2018

According to Amez, there are a number of skincare products containing Syn-Ake available on the market. The most affordable (at $14.80) is the “Buffet” serum by The Ordinary, which contains Syn-Ake in its peptide-blend.

The rest are much more expensive. “I’m most familiar with MBR, a German-engineered product line focused on high-active, high-potency ingredients,” she explains. “The MBR Cross Lift Ultra Peptide Serum is just under $450 and works to prohibit micro contractions. When paired with the MRB Liquid Surgery Serum, which costs $1,800, it’s a topical equivalent to Botox or even a face lift, putting the cost into perspective a bit. Interestingly enough, though, MBR doesn’t market the product based on it’s Syn-Ake at all. For MBR, it’s just another one of its state-of-the-art ingredients.”

Other brands are a lot less subtle. For instance, Rodial, a globally renowned skincare brand, has an entire line of Syn-Ake products — from Snake Neck Masks ($22), to Snake Serum ($94), to Snake Booster Oil ($76.50), to Snake Eye Cream ($59.50). The official product photography for these products feature them tucked in the curl of a snake’s body, with, naturally, the snake’s tongue out, to be extra sure to hype the “venom” of it all. It’s still, though, not as over-the-top as some of the Russian/Thai/Etc. cheaper versions:

Rodial also has a bee venom line (packaged in yellow) — e.g., Bee Venom Moisturizer ($200.95), Bee Venom Cleansing Balm ($81.65) and a Bee Venom Taster Kit ($56.52). In these products, however, the active ingredient isn’t a synthetic compound but actual venom. It, too, is based on legit science, as bee venom has anti-inflammatory properties, making it good for acne and capable of being turned into peptides with anti-aging benefits.

As David Yi, founder of the men’s grooming and beauty site Very Good Light, explains, “Bee venom (i.e., apitoxin) is what comes out of a bee’s stinger. Every bee sting has around 0.1 milligrams of venom, which causes inflammation of your skin with blood rising to its surface. That immediately signals to your skin to regenerate, producing collagen, which, in turn, creates younger, radiant and plumper skin. While it’s a wonder product — we lose about 1 percent of collagen every year when we get to 20 — we need to ensure bees are treated ethically. For this, you need to see how the venom is sourced and to make sure that it’s extracted without compromising, you know, the bees’ lives.”

Richard Walker, the founder of an expert serums company called skinChemists, told Refinery29 in 2017 the ethical way to do so is as follows: “The process works by attracting bees to a glass pane, which has a small electrical current running through it. The bees are encouraged to sting the glass, leaving behind small traces of bee venom but not losing their stinger.” (It’s crazy to add, but humans have also died attempting to try Goop-endorsed bee-sting thearpy methods for anti-inflammation; though, it’s important to note that this had nothing to do with the creams mentioned above.)

As for Rodial’s Dragon’s Blood line? That stuff’s derived from a tree, not a fantastical beast.

Or at least so they say.

Tierney Finster

Tierney Finster is a journalist, screenwriter, actor and model from Los Angeles, California. She is a contributing writer at MEL, specializing in love, sex, mental health, drugs, queer culture and the cannabis industry. She has written for publications such as Playboy, Purple, Dazed and Confused, Jezebel and Broadly and was the key researcher behind Sex On, HBO’s revival of its iconoclastic docu-series Real Sex.

Snake venom anti-ageing cream is sell-out hit

An anti-ageing skin cream which mimics the effects of snake venom, has become a best-seller since its launch last week in Selfridges.

Planet Skincare costs £60, and incorporates synthesised snake venom, which mimics the effect of a snakebite. Skin is left in a stunned state, as it would be if attacked by the reptile; an effect similar to that of Botox.

The formula was developed to mimic the venom of the Temple Viper snake.

The makers claim that the product visibly reduces lines and wrinkles in 28 days, with a 52% reduction in wrinkles and 82% increase in skin smoothness.

It first hit the shelves of Selfridges last week, and has since been selling 50 pots every day, to quickly become one of the store’s best-selling premium beauty products.

Speaking to the Daily Mail, Christine Benson, of Selfridges beauty, said, ‘Products containing snake venom have been used for a few months now in the US, actresses especially love the effect. Unlike Botox it allows the face movement and emotion, but lessens wrinkles and paralyses muscles which cause creases.’

To buy the cream online, .

Should You Be Putting Venom On Your Skin?

Simply Venom

When it comes to skin-care ingredients, there are your standard suspects: antioxidants, vitamins, peptides, retinoids, and different botanicals. Then there are the much stranger options which always make us take pause (bird poop and snail mucus are among some of the more bizarre celeb beauty trends we’ve seen). So when we noticed that more and more products were touting venom, we had to wonder which category this trendy ingredient fell into. Is this all just a gimmick, or could it be that these “poisonous” products will soon join the ranks of proven anti-agers?

First and foremost, it’s important to know what kind of venom is being used. Bee venom (yes, from actual bees) is common, and has some science behind it, according to NYC-based celebrity dermatologist, Whitney Bowe, M.D. “The studies are small, but they’re promising and intriguing. They indicate that honey bee venom can be helpful in treating acne because it’s antibacterial; eczema because it’s anti-inflammatory; and anti-aging because it may help with collagen production,” she says. You can find it in any number of products, from masks (like Miss Spa Bee Venom Plumping Sheet Mask, $8; to oils (Manuka Doctor Drops of Crystal Beautifying Bi-Phase Oil $26; to creams (Beenigma Cream, $53;

What about when you see snake “venom” listed in products like Rodial Snake Eye Cream ($95; and Simply Venom Day Cream ($59; It’s typically a synthetic blend of proprietary peptides that promise to paralyze the muscle, the basic premise behind topical venom, says Dr. Bowe. In theory, this inhibits the muscle contractions that can, over time, lead to the formation of wrinkles and lines. But take that claim with a grain of salt: “There’s not a lot of evidence showing that venom actually does inhibit muscle activity long enough to work as well as an injectable neurotoxin, like Botox,” Bowe explains. “The effects of the venom are transient and weak, lasting anywhere from 15 minutes to a few hours, which won’t permanently stop the muscle movement.”

Still, if you’re needle-phobic, are focused more on prevention than reversal, or don’t have crazy high expectations, these venom-infused topicals can be a good alternative, says Dr. Bowe. And while they may not be a direct replacement for injectables, they can help prolong their effects when used as an adjunct treatment, she adds.

Regardless, any kind of venom stimulates circulation, bringing blood flow to the area. While that can be painful when it comes to a bee sting, it’s a good thing when it comes to your complexion, as increased blood flow can plump the skin and leave it glowing. The bottom line? There’s no need to be scared of these poisonous products, and it may be worth incorporating one or two into your skin-care stash-just be realistic about their promises and your expectations.

  • By By Melanie Rud Chadwick

The cream is saturated with revitalizing ingredients for intensive skin care at night. Its formula is based on the unique tripeptide SYN®-AKE which structure repeats the structure of the paralyzing protein of the venom of the temple viper. It blocks the transmission of nerve impulses to the facial muscles which leads to their relaxation and smoothing of mimic wrinkles.
The smoothing effect of the cream with 4% SYN®-AKE content has been clinically proven:

  • up to 8% smoothing of wrinkles in the area of ​​“crow’s feet” *
  • up to 21% smoothing of wrinkles on the forehead *
  • 80% of users indicated a smoothing effect *

* according to DSM test results (Switzerland)
The cream smoothes the skin, returns to face fresh, rested appearance.
Active ingredients:

  • SYN®-AKE, an analogue of the temple viper poison peptide (4%)
  • Hydrovance® moisturizing complex
  • Hyaluronic acid
  • Cotton oil
  • Coconut oil


  • Relaxes facial muscles, effectively smoothes wrinkles
  • Keeps skin hydrated for long time
  • Nourishes and softens
  • Leaves skin smooth and velvety

Application: Apply the cream on clean skin in the evening with light knocking movements. In areas of severity of wrinkles (“crow’s feet”, nasolabial folds, on the forehead) – carefully massage the skin until the cream is completely absorbed. The cream is suitable for the neck and décolleté. For maximum effect use in combination with Day Face Cream with Snake Venom Peptide for Intensive Correction of Wrinkles 40+.

Best Revive Derma Snake Venom Peptide Cream of 2020 – Top Rated & Reviewed

Product Names Product Images Check Price

#1 Anti Aging Face Cream Enriched with Collagen Boosting Peptides, Hyaluronic Acid, Coenzyme Q10, Organic Aloe, Coconut Oil, MSM, Vitamins C and B5 – Face Moisturizer Repairs, Protects and Hydrates Skin

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#2 DERMA E Advanced Peptide & Collagen Moisturizer

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#3 TruSkin Vitamin C-Plus Super Serum, Anti Aging Anti-Wrinkle Facial Serum with Niacinamide, Retinol, Hyaluronic Acid, and Salicylic Acid, 1 oz

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#4 Peptide Complex Serum by Eva Naturals (2 oz) – Best Anti-Aging Face Serum Reduces Wrinkles and Boosts Collagen – Heals and Repairs Skin while Improving Tone and Texture – Hyaluronic Acid & Vitamin E

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#5 Syn-ake Snake Botox DNA Serum | Anti Wrinkle Snake Venom Cream with Syn-ake

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#6 DERMA E Advanced Peptides and Collagen Eye Cream, 1/2oz

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#7 DERMA E Advanced Peptides & Collagen Serum, 2oz

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#8 3 Peptide Firming Serum For Skin & Face With Hyaluronic Acid & Collagen – Anti Aging, Repair Wrinkles & Tightens Neck & Eyes, Reduces Dark Spots, Step 1

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#9 Botox Alternative- -Snake Peptide, Palmitoyl Tripeptide-5 Peptide , 5% Vitamin B3 Niacinamide, B5, E , C & 1% Retinol Dmae ,Hyaluronic Acid Anti-aging, Best Wrinkle Cream, Serum Repair, Boost Collagen 1.oz Pump

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#10 Eye Gel Anti-Aging Cream – Treatment for dark Circles, Puffiness, Wrinkles and Fine Lines – Hyaluronic Acid Formula Infused Serum with Aloe Vera & Jojoba for Ageless Smooth Skin

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* may collect a share of sales or other compensation from the links on this page.

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  • What is the best Revive Derma Snake Venom Peptide Cream for 2019, for 2018 or even 2017 (old models)?
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  • or even What is the best affordable (best budget, best cheap or even best expensive!!!) Revive Derma Snake Venom Peptide Cream?…

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Before deciding to buy any stuffs, make sure you research and read carefully the buying guide somewhere else from trusted sources. Good news, we use Big Data and AI to solve the issue. We use our own invented, special algorithms to generate lists of the best brands and give them our own Scores to rank from 1st to 10th.

You could see the Top 10 Revive Derma Snake Venom Peptide Cream of 2019 above. The lists of best items are updated regularly, so you can be sure that the information provided is up-to-date.

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